Sealkleen filters, with a Pall-innovated design that eliminates the risk of bypass from upstream to downstream, are single-use filter cartridges to be used with purpose-designed in-line stainless steel housings. They are ideally suited for filtration requirements in small to medium-sized GMP manufacturing operations (30 L to 500 L).

These 0.45 micron-rated filters are predominantly used in pre-filtration applications or viscous fluid filtrations. Validated removal of Serratia marcescens (ATCC 14756) with a typical titer reduction (TR) of > 106 ensures that they are also suitable for bioburden control. A serial layer (0.65/0.45 micron) membrane construction allows for high throughputs and high flow rates compared with other 0.45 micron-rated filters.

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